Biologic medicines

Biological medicines are a form of treatment for Crohn’s Disease and Ulcerative Colitis (the two main forms of Inflammatory Bowel Disease - IBD). In general they are prescribed for people with moderate to severe Crohn's or Colitis when other treatments have not worked. 

Deciding to take a biologic medicine can feel like a big step. But if you’re not well and other treatments aren’t working, they can make a huge difference to your quality of life. Whether you’ve been prescribed a biologic for Crohn’s or Colitis or you’re considering it as an option, this information sheet is for you.

It looks at:
• the different biologics available for Crohn’s Disease and Ulcerative Colitis
• how the medicines work
• stopping or changing treatment
• biosimilars.

What is a biologic medicine?
What biologic medicines are used to treat Crohn's or Colitis?
How do biologic medicines work?
What can I expect from treatment?
How do I take biologic medicines?
Making treatment choices
Stopping or changing treatment
What is a biosimilar?
Questions you may have about biosimilar medicines
Starting treatment with a biologic medicine
Help and support from Crohn's & Colitis UK
How we write our information

Last reviewed: June 2019

Last amended: February 2020