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Treatment for Crohn’s Disease and Ulcerative Colitis depends on how severe the symptoms are, and how much of the gut is affected. 

selection of pills and pill bottles
Last reviewed March 2022

There are many different treatments available to help you live well with your Crohn’s or Colitis. Together with your IBD team, you can decide what treatment is right for you.

At first, medicines aim to reduce inflammation in the gut to bring about remission. Remission is when you feel better and your Crohn's or Colitis symptoms aren't bothering you. Once the condition is under control, your doctor will usually continue to prescribe drugs to maintain remission and prevent relapse (feeling unwell again) – this is called maintenance treatment.

Medicines to treat Crohn's and Colitis

Immunosuppressant medicines
These medicines control the immune system to stop it attacking the gut:

Other medicines


Sometimes people with Crohn's or Colitis require surgery. A range of surgeries can be recommended and these guides looks at what they are and when they are necessary, weighing up the pros and cons in the process:

Other forms of treatment

Browse our list of free booklets, information sheets and guides for detailed information about other forms of treatment for Crohn’s and Colitis, including dietary therapy, counselling and controlling fatigue.


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Helpline service


We know it can be difficult to live with, or support someone living with these conditions. But you’re not alone. We provide up-to-date, evidence-based information and can support you to live well with Crohn’s or Colitis.

Our helpline team can provide information on a range of subjects including:

  • Managing Symptoms
  • Disability benefits
  • Medication
  • Diet
  • Test and diagnosis
  • Wellbeing
  • Employment
  • Help to find support from others living with the condition

Please contact us via telephone, email or LiveChat - 9am to 5pm, Monday to Friday (except English bank holidays).

If you need specific medical advice about your condition, your GP or IBD team will be best placed to help.