A new platform for perianal Crohn’s fistula research

Perianal fistulas are a common complication of Crohn’s Disease.  A fistula is when a tunnel develops that connects an organ to another part of your body. Perianal fistulas connect the anal canal or rectum to the surface of the skin near the anus, where poo leaves the body. These fistulas are often very painful and can leak blood, pus and poo.

It is hard to manage and treat perianal fistulas. Even with treatment and surgery, some fistulas do not heal.

The researchers have found that there is a need for more research into improving outcomes and quality of life of patients with perianal Crohn’s.

What this research is looking at

The researchers have set up a study called GONDOMAR- GOals, Needs and Determinants Of Multimodal therapy in periAnal cRohn’s fistula. This study will recruit and follow over 4000 patients with perianal fistulas from over 80 hospitals or clinics across the UK. GONDOMAR will be developed into a research platform where different hospitals and clinics in the UK can share their learning and knowledge around perianal fistulas and identify best practice to improve outcomes for patients.

What the researchers think this could mean for people with Crohn's and Colitis

The researchers expect that this study will collect a large amount of data to help them learn more about perianal Crohn’s fistulas. The researchers think GONDOMAR will lead to:

• Improve understanding and diagnosis of perianal Crohn’s fistula and find new treatment options.
• Look at what medicine options work best to treat symptoms and repair and heal fistulas.
• Understand and improve the goals and quality of life for people living with perianal Crohn’s fistulas.
• Undertake further research around perianal Crohn’s.

Who is leading this research: Professor Shaji Sebastian

Our funding: £92,275

Duration: 36 months

Official title of application: GONDOMAR Platform: GOals, Needs and Determinants Of Multimodal therapy in periAnal cRohn’s Fistula- A platform for fistula research